November 19 | 2014


Structural insight into cap-snatching and RNA synthesis by influenza polymerase

Authors |Stefan Reich, Delphine Guilligay, Alexander Pflug, Hélène Malet, Imre Berger, Thibaut Crépin, Darren Hart, Thomas Lunardi, Max Nanao, Rob W. H. Ruigrok & Stephen Cusack

November 19 | 2014



Structure of influenza A polymerase bound to the viral RNA promoter


Video: Structure of complete flu polymerase

Authors | Pflug, Guilligay, Reich & Cusack

June 4 | 2014


PB2 Mutations D701N and S714R Promote Adaptation of an Influenza H5N1 Virus to a Mammalian Host

Interaction of amino acids 701 and 714 with the NLS in the C-terminal 524 domain of PB2 (modelling by Mikhail Matrosovich)


Authors | Czudai-Matwich V, Otte A, Matrosovich M, Gabriel G, Klenk HD

May 14 | 2014


Importin-α7 is Required for Enhanced Influenza A Virus Replication in the Alveolar Epithelium and Severe Lung Damage in Mice

Authors |Resa-Infante P, Thieme R, Ernst T, Arck PC, Ittrich H, Reimer R, Gabriel G

April 15 | 2014

Flupharm’s third annual meeting in Hamburg

Flupharm scientists and science advisory board all met 9-11 April in Hamburg for an annual progress meeting and review.